| Primary Identifier | MGI:2681436 | Allele Type | Targeted |
| Gene | Igh-J | Transmission | Germline |
| Strain of Origin | C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The endogenous DQ52 and all four heavy chain J elements were replaced by the rearranged heavy chain VDJ region of hybridoma KL25 5.8 (for a LCMV-neutralizing antibody) and a floxed neomycin resistance cassette. The neomycin cassette was removed in vivo by breeding to Cre deleter mice. This allele is expressed in more than 95% of all B cells. |
