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Allele : Rag1<tm1Fwa> recombination activating 1; targeted mutation 1, Frederick W Alt

Primary Identifier  MGI:2681693 Allele Type  Targeted
Gene  Rag1 Transmission  Germline
Strain of Origin  129S6/SvEvTac Is Recombinase  false
Is Wild Type  false
molecularNote  The Rag1 coding sequence was replaced with a truncated core Rag-1 sequence followed by a floxed neomycin resistance gene. The neomycin gene was then removed from properly targeted ES cells by transient transfection with a plasmid based Cre recombinase. Core Rag1 was expressed at levels comparable to that found for intact protein.
  • mutations:
  • Insertion
  • synonyms:
  • R1core,
  • RAG1<c>,
  • RAG1<c>,
  • R1core
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

38 Publication categories