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Allele : Prnp<tm1(PRNP)Tkit> prion protein; targeted mutation 1, Tetsuyuki Kitamoto

Primary Identifier  MGI:2681980 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Prnp
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  The majority of the endogenous mouse gene was replaced with mutant human PRNP sequence. The human sequence contained a nonsense mutation at codon 145. 3' mouse sequence remained downstream of the inserted human sequence.
  • mutations:
  • Insertion
  • synonyms:
  • Hu-Ki,
  • Ki-ChM,
  • Hu-Ki,
  • Ki-ChM
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

6 Publication categories