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Allele : Pdgfrb<tm7Sor> platelet derived growth factor receptor, beta polypeptide; targeted mutation 7, Philippe Soriano
Primary Identifier  MGI:2682372 Allele Type  Targeted
Attribute String  Not Specified Gene  Pdgfrb
Transmission  Germline Strain of Origin  129S4/SvJaeSor
Is Recombinase  false Is Wild Type  false
molecularNote  A point mutation was engineered and incorporated in codon 770 of the endogenous locus via homologous recombination. The mutation results in a tyrosine to phenylalanine substitution (Y770F) at a site crucial for RasGAP signal transduction.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • F1,
  • F1
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

4 Publication categories





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