Primary Identifier | MGI:2682061 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Ext1 |
Transmission | Germline | Strain of Origin | 129S5/SvEvBrd |
Is Recombinase | false | Is Wild Type | false |
description | Phenotypic Similarity to Human Syndrome: Peters Anomaly in homozygous mice carrying Tg(Wnt1-cre)11Rth (J:152572) |
molecularNote | The coding region of exon 1 was flanked by single loxP sites in the 5' untranslated region of exon 1 and in intron 1. The targeting vector contained a frt-flanked neomycin cassette in intron 1, though this selection cassette was removed via in vivo FLP-mediated recombination. |