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Allele : Lamc1<tm1Strl> laminin, gamma 1; targeted mutation 1, Sidney Strickland

Primary Identifier	MGI:2683482	Allele Type	Targeted
Attribute String	Conditional ready, Hypomorph	Gene	Lamc1
Transmission	Germline	Strain of Origin	129P2/OlaHsd
Is Recombinase	false	Is Wild Type	false

molecularNote

Exon 2 was flanked by single loxP sites. An frt flanked neo cassette was inserted upstream of the floxed region, in intron 1. This allele is hypomorphic.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
LAMC1fl<neo>,
LAMC1fl<neo>,
fLAMgamma1,
Lamgamma1 KO,
Lamgamma1 KO,
fLAMgamma1

earliestPublication:
Chen ZL, et al. (2003) Laminin gamma1 is critical for Schwann cell differentiation, axon myelination, and regeneration in the peripheral nerve. J Cell Biol 163(4):889-99

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

20 Publication categories

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