| Primary Identifier | MGI:2682818 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Esrra |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 2, which encodes the amino-terminal region and an essential component of its DNA-binding domain, was replaced with a neomycin selection cassette inserted by homologous recombination. The deleted exon encoded the N-terminal region and a zinc finger domain. Northern blot analysis of renal RNA and Western blot analysis of intestinal protein indicated an absence of normal gene product in homozygous mutant mice. |
