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Allele : Tg(Ins2-CD80)3B7Flv transgene insertion 3B7, Richard Flavell
Primary Identifier  MGI:2682826 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Ins2-CD80)3B7Flv
Strain of Origin  (C57BL/6 x CBA/Ca)F2 Is Recombinase  false
Is Wild Type  false
description  Mice carrying this transgene that also are homozygous for Prkdcscid are characterized by pancreatic beta cells that express a rat insulin II promoter regulated transgene encoding the human CD80 T cell co-stimulatory molecule.
molecularNote  The transgene contains a human CD80 antigen gene driven by the rat insulin II promoter (Ins2).
  • mutations:
  • Insertion
  • synonyms:
  • RIP-B7,
  • RIP-B7-1,
  • RIP-CD80,
  • RIP-B7.1,
  • RIP-B7.1,
  • RIP-B7,
  • RIP-CD80,
  • RIP-B7-1
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

9 Carried By

1 Driven By

30 Publication categories





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