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Allele : Pparg<tm1.1Auw> peroxisome proliferator activated receptor gamma; targeted mutation 1.1, Johan Auwerx

Primary Identifier  MGI:2683413 Allele Type  Targeted
Gene  Pparg Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  The frt flanked neomycin selection cassette was excised from Ppargtm1Auw via FLP mediated recombination. The proline to alanine missense mutation at codon 12 (exon B) was left intact. The levels of both Pparg1 and Pparg2 transcript in homozygous mutant mice did not significantly differ from those of wild-type.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • PPARgamma<Pro12Ala>,
  • PPARgamma<Pro12Ala>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

6 Publication categories