First Author | Akeson EC | Year | 2006 |
Journal | Genomics | Volume | 87 |
Issue | 2 | Pages | 311-3 |
PubMed ID | 16309882 | Mgi Jnum | J:105810 |
Mgi Id | MGI:3616719 | Doi | 10.1016/j.ygeno.2005.09.022 |
Citation | Akeson EC, et al. (2006) Chromosomal inversion discovered in C3H/HeJ mice. Genomics 87(2):311-3 |
abstractText | Mice of the inbred mouse strain C3H/HeJ have been shown to be homozygous for a chromosomal inversion on Chromosome (Chr) 6. The inversion encompasses about 20% of the chromosome from approximately 73 Mb to approximately 116 Mb. The importance of this finding is that linkage crosses using C3H/HeJ will show no recombination in this region of Chr 6. The inversion has no apparent effect on the phenotype of C3H/HeJ mice and its presence should not affect biological studies; however, use of C3H/HeJ mice for genetic analysis of Chr 6 should be avoided or the results interpreted with the inversion in mind. The inversion has been named In(6)1J (inversion Chr 6, Jackson 1). |