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Publication : Chromosomal inversion discovered in C3H/HeJ mice.

First Author  Akeson EC Year  2006
Journal  Genomics Volume  87
Issue  2 Pages  311-3
PubMed ID  16309882 Mgi Jnum  J:105810
Mgi Id  MGI:3616719 Doi  10.1016/j.ygeno.2005.09.022
Citation  Akeson EC, et al. (2006) Chromosomal inversion discovered in C3H/HeJ mice. Genomics 87(2):311-3
abstractText  Mice of the inbred mouse strain C3H/HeJ have been shown to be homozygous for a chromosomal inversion on Chromosome (Chr) 6. The inversion encompasses about 20% of the chromosome from approximately 73 Mb to approximately 116 Mb. The importance of this finding is that linkage crosses using C3H/HeJ will show no recombination in this region of Chr 6. The inversion has no apparent effect on the phenotype of C3H/HeJ mice and its presence should not affect biological studies; however, use of C3H/HeJ mice for genetic analysis of Chr 6 should be avoided or the results interpreted with the inversion in mind. The inversion has been named In(6)1J (inversion Chr 6, Jackson 1).
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