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Publication : 'Green mice' as a source of ubiquitous green cells.

First Author  Okabe M Year  1997
Journal  FEBS Lett Volume  407
Issue  3 Pages  313-9
PubMed ID  9175875 Mgi Jnum  J:87415
Mgi Id  MGI:2686880 Doi  10.1016/s0014-5793(97)00313-x
Citation  Okabe M, et al. (1997) 'Green mice' as a source of ubiquitous green cells. FEBS Lett 407(3):313-9
abstractText  The green fluorescent protein (GFP) is responsible for the green bioluminescence of the jellyfish Aequorea victoria. Many classes of GFP mutants exist that display modified fluorescence spectra and an increased extinction coefficient. We produced transgenic mouse lines with an 'enhanced' GFP (EGFP) cDNA under the control of a chicken beta-actin promoter and cytomegalovirus enhancer. All of the tissues from these transgenic lines, with the exception of erythrocytes and hair, were green under excitation light. The fluorescent nature of the cells from these transgenic mouse lines would facilitate their use in many kinds of cell transplantation experiments.
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