| Primary Identifier | MGI:2687368 | Allele Type | Spontaneous |
| Attribute String | Hypomorph | Gene | Txnip |
| Inheritance Mode | Dominant | Strain of Origin | HcB19/Dem |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A T-to-A transversion mutation at coding nucleotide 291 in the 1,456-bp cDNA results in a tyrosine (TAT) to a stop codon (TAA) alteration at amino acid 97 (p.Y97*) in the encoded protein. This mutation was absent in the C3H parental strain and all other strains observed. A decreased level of mutant transcript was expressed from this allele. |
