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Allele : Adam19<Gt(Betageo)1Bbl> ADAM metallopeptidase domain 19; gene trap 1, Carl P Blobel

Primary Identifier  MGI:3028702 Allele Type  Gene trapped
Attribute String  Null/knockout, Reporter Gene  Adam19
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Sequence encoding the carboxyl cysteine-rich domain was disrupted by a secretory gene trap vector containing a Beta-geo cassette. The insertion putatively interferes with proper protein folding resulting in the retention and subsequent degradation of the mutant protein in the enodplasmic reticulum.
  • mutations:
  • Insertion of gene trap vector
  • synonyms:
  • adam19<->,
  • adam19<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

6 Publication categories