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Allele : Was<tm1Kas> Wiskott-Aldrich syndrome; targeted mutation 1, Katherine A Siminovitch

Primary Identifier	MGI:3028420	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Was
Transmission	Germline	Strain of Origin	(129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase	false	Is Wild Type	false

molecularNote

The sequence from intron 4 to exon 11 was replaced with a neomycin resistance gene. Immunoblot analysis demonstrated that no protein expression occurred.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

synonyms:
WASp<->,
WASp<->,
WAS<->,
WAS<->

earliestPublication:
Zhang J, et al. (1999) Antigen receptor-induced activation and cytoskeletal rearrangement are impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytes. J Exp Med 190(9):1329-42

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

17 Publication categories

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