| Primary Identifier | MGI:3028848 | Allele Type | Transgenic |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(aP2-SREBF1c)9884Reh |
| Strain of Origin | (C57BL/6J x SJL)F2 | Is Recombinase | false |
| Is Wild Type | false |
| description | This line was generated from founder number 988-4. |
| molecularNote | Sequence encoding residues 1 through 436 of human nuclear sterol regulatory element binding protein-1c (SREBF1c) was adjoined to 5.4 kb of the mouse adipose-specific enhancer/promoter of aP2. SREBF1c sequence encoding the membrane-attachment domain was not included in the construct, permitting the expressed component to enter the nucleus without a requirement for proteolysis. |
