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Allele : Tg(MMTV-Catnb)3Pac transgene insertion 3, Pamela Cowin

Primary Identifier  MGI:3029662 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(MMTV-Catnb)3Pac
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  To express catenin beta in the epithelium of the mammary ducts, cDNA encoding Xenopus catenin beta was adjoined to a mouse mammary tumor virus long terminal repeat. The encoded catenin beta protein lacks 89 amino terminal residues, retains cadherin/catenin binding, and has increased stability in the cytoplasmic pool. Beta globin sequence and a myc epitope tag were also included in the construct. Founder mice contained a single copy of the construct and were considered "low expressing" relative to line 5.
  • mutations:
  • Insertion
  • synonyms:
  • MMTV-DeltaN89Beta-catenin,
  • MMTV-DeltaN89Beta-catenin
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories

Trail: Allele