Primary Identifier | MGI:3029862 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Adar |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A genomic fragment encompassing exons 2 through 13 was replaced with a neo cassette inserted by homologous recombination. The deleted region encodes residues 11 through 1054, which encompass the all three dsRNA-binding domains, two putative Z-DNA-binding domains, and the majority of the catalytic domain. |