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Allele : Stat3<tm1Dnl> signal transducer and activator of transcription 3; targeted mutation 1, James E Darnell

Primary Identifier  MGI:3028651 Allele Type  Targeted
Gene  Stat3 Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  In order to ablate serine phosphorylation at codon 727, a serine to alanine substitution mutation was introduced into exon 23 at codon 727 via homologous recombination. A floxed neo cassette inserted downstream of the polyadenylation signal was excised via cre-mediated recombination.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Stat3 S727A,
  • Stat3 S727A,
  • SA,
  • SA,
  • STAT3SA-,
  • STAT3SA-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

15 Publication categories

Trail: Allele