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Allele : Foxl2<tm1Tre> forkhead box L2; targeted mutation 1, Mathias Treier

Primary Identifier  MGI:3029503 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Foxl2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  The sequence encoding amino acids 62-375 was replaced with an in frame nls-lacZ cassette followed by a floxed neomycin resistance gene. This deletes almost the entire the forkhead/winged-helix domain. The neomycin gene was subsequently excised. Western blot analysis of protein extracts from neonatal ovaries detected only lacZ fusion proteins and not the wild-type protein.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Foxl2<lacZ>,
  • Foxl2<lacZ>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

10 Publication categories