|  Help  |  About  |  Contact Us

Allele : Tg(MMTV-Catnb)5Pac transgene insertion 5, Pamela Cowin

Primary Identifier  MGI:3029682 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(MMTV-Catnb)5Pac
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  To express catenin beta in the epithelium of the mammary ducts, cDNA encoding Xenopus catenin beta was adjoined to a mouse mammary tumor virus long terminal repeat. The encoded catenin beta protein lacks 89 amino terminal residues, retains cadherin/catenin binding, and has increased stability in the cytoplasmic pool. Beta globin sequence and a myc epitope tag were also included in the construct. Founder mice contained approximately 45 copies of the construct and were considered "high expressing" relative to line 3.
  • mutations:
  • Insertion
  • synonyms:
  • MMTV-DeltaN89Beta-catenin,
  • MMTV-DeltaN89Beta-catenin
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories

Trail: Allele