| First Author | Adler DA | Year | 1995 |
| Journal | Mamm Genome | Volume | 6 |
| Issue | 8 | Pages | 491-2 |
| PubMed ID | 8589515 | Mgi Jnum | J:28085 |
| Mgi Id | MGI:75714 | Doi | 10.1007/BF00356163 |
| Citation | Adler DA, et al. (1995) The X-linked methylated DNA binding protein, Mecp2, is subject to X inactivation in the mouse. Mamm Genome 6(8):491-2 |
| abstractText | DNA methylation at the promoter region of X-linked genes is associated with the maintenance of X inactivation in mammals. One of the methylated DNA binding proteins, MECP2, that binds to methylated bases in DNA is encoded by a gene (Mecp2) located on the mouse X Chromosome (Chr). To determine whether this gene was expressed from the inactive X Chr, and X-autosome translocation (T(X;16)16H) system in which expression from the Mecp2 allele on the inactive X Chr could be assayed was used. Results from these experiments indicate that Mecp2 is subject to X inactivation in mouse. |
