|  Help  |  About  |  Contact Us

Allele : Gli2<tm5.1(GLI3)Alj> GLI-Kruppel family member GLI2; targeted mutation 5.1, Alexandra L Joyner
Primary Identifier  MGI:3032719 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Gli2
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  The floxed neo cassette was excised from Gli2tm5(GLI3)Alj, leaving the human GLI3 cDNA, flanked with an upstream FLAG epitope and a downstream mouse Gli2 3' UTR and three tandem repeats of a SV40 polyA signal, positioned within the first coding exon of the endogenous Gli2 locus. Western blot analysis of mutant mice indicated that the full length and the repressor form of the GLI3 protein were present. The level of GLI3 expression from this allele was reported to be greater than from Gli2tm5(GLI3)Alj.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Gli2<3ki>,
  • Gli2<3ki>
Paste the following link
Quick Links:
SummaryGenomePhenotypeOther
 
Quick Links:
SummaryGenomePhenotypeOther
 
Lists
This Allele isn't in any lists. Upload a list.

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories





MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom