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Allele : Icmt<tm1Mbrg> isoprenylcysteine carboxyl methyltransferase; targeted mutation 1, Martin O Bergo

Primary Identifier  MGI:3033709 Allele Type  Targeted
Attribute String  Conditional ready, Hypomorph Gene  Icmt
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neomycin resistance gene was inserted upstream of exon 1 while a third loxP site was inserted in intron 1. Expression and activity levels of the encoded protein were 70 to 90% lower than controls.
  • mutations:
  • Insertion
  • synonyms:
  • Icmt<flx>,
  • Icmt<hm>,
  • Icmt<hm>,
  • Icmt<flx>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

10 Publication categories