Primary Identifier | MGI:3033711 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Adh5 |
Transmission | Germline | Strain of Origin | 129 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Homologous recombination was used to replace exons 5 and 6 with a neomycin resistance gene. The deleted region encoded most of the coenzyme binding domain. S-nitrosoglutathione reductase activity was undetected in various tissues obtained from homozygous mutant mice. |