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Allele : Adh5<tm1Stam> alcohol dehydrogenase 5 (class III), chi polypeptide; targeted mutation 1, Jonathan S Stamler

Primary Identifier  MGI:3033711 Allele Type  Targeted
Attribute String  Null/knockout Gene  Adh5
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  Homologous recombination was used to replace exons 5 and 6 with a neomycin resistance gene. The deleted region encoded most of the coenzyme binding domain. S-nitrosoglutathione reductase activity was undetected in various tissues obtained from homozygous mutant mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • GSNOR<->,
  • GSNOR<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

37 Publication categories