Primary Identifier | MGI:3036096 | Allele Type | QTL |
Gene | Kif1c | Inheritance Mode | Dominant |
Strain of Origin | DBA/2J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Mapping experiments restricted the QTL region to a restricted region in which Kif1c is the most likely candidate gene for the experimental autoimmune orchitis trait. Further, insertion of a transgene containing the resistance allele of this QTL to the susceptible background reduced susceptibility. This allele confers orchitis resistance compared to BALB/cByJ. |