| Primary Identifier | MGI:3036671 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Sox3 |
| Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The endogenous coding region was replaced with a construct containing floxed Sox3 sequence followed by GFP and frt-flanked neo. The floxed Sox3 sequence was removed via cre-mediated recomibination in the germline, leaving GFP downstream of the endogenous promoter. Mutant XY embryos expressed GFP, but not Sox3, in a pattern consistent with that of endogenous Sox3 expression in wild-type mice. This allele was derived from Sox3tm2Rlb |
