| Primary Identifier | MGI:3036561 | Allele Type | Targeted |
| Gene | Myog | Transmission | Germline |
| Strain of Origin | 129/Sv | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | To disrupt phosphorylation of the encoded protein at threonine 87, a threonine-to-asparagine substitution mutation was engineered in the basic DNA-binding region at codon 87 (T87N) of exon 1. A single frt site remained in intron after the excision of an frt-flanked neo cassette from the germline. Expression of the mutant transcript was verified by Northern blot analysis of homozygous mutant mice. |
