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Allele : Gata1<tm6Sho> GATA binding protein 1; targeted mutation 6, Stuart Orkin
Primary Identifier  MGI:3037864 Allele Type  Targeted
Attribute String  Null/knockout Gene  Gata1
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A high-affinity, palindromic "double" GATA protein binding site in the Gata1 promoter presumed to mediate positive Gata1 autoregulation was replaced by a floxed Pgk-neo cassette; transient Cre recombinase expression in ES cells left a single loxP site flanked by two Not1 sites. The 21-bp deleted segment comprised nucleotides -691 through -671 upstream of the last nucleotide of the first hematopoietically expressed exon of Gata1.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Gata1<tm5Sho>,
  • deltadblGATA,
  • deltadblGATA,
  • Gata1<tm5Sho>,
  • dblGATA1,
  • Eos<->,
  • deltadbl GATA,
  • dblGATA1,
  • deltadbl GATA,
  • Eos<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

4 Carried By

0 Driven By

115 Publication categories





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