| Primary Identifier | MGI:3038659 | Allele Type | QTL |
| Gene | Hdlq15 | Inheritance Mode | Not Specified |
| Strain of Origin | 129S1/SvImJ | Is Recombinase | false |
| Is Wild Type | false |
| description | Hdlq14 and Hdlq15 interact. Homozygosity for C57BL/6J-derived alleles at Hdlq14 and homozygosity for 129S1/SvImJ-derived alleles at Hdlq15 confers decreased HDL cholesterol levels. Hdlq58 and Hdlq15 interact. Homozygosity for 129S1/SvImJ alleles at Hdlq15 in conjunction with homozygosity for C57BL/6J alleles at Hdlq58 confers increased plasma HDL cholesterol concentration in animals fed a CHOW diet. Hdlq60 and Hdlq15 interact. Homozygosity for 129S1/SvImJ alleles at Hdlq15 in conjunction with at least one C57BL/6J allele at Hdlq60 confers significantly increased plasma HDL in animals fed an atherogenic diet. |
| molecularNote | This allele confers increased HDL cholesterol levels on an atherogenic diet compared to C57BL/6J. |
