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Allele : Il1rn<tm1Nick> interleukin 1 receptor antagonist; targeted mutation 1, Martin J H Nicklin

Primary Identifier  MGI:3038876 Allele Type  Targeted
Attribute String  Null/knockout Gene  Il1rn
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Homologous recombination was used to fuse a vector containing the aph gene driven by a beta actin promoter with the ORF at exon 3, which encodes the single folding domain. This is codon 77 in the secreted form of the endogenous protein or codon 82 of the intact cell form. RT-PCR revealed that no transcript was found in mutant peritoneal macrophages.
  • mutations:
  • Insertion
  • synonyms:
  • Il1rn<->,
  • Il1rn<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

15 Publication categories