| Primary Identifier | MGI:3039264 | Allele Type | Targeted |
| Gene | Trp53 | Transmission | Germline |
| Strain of Origin | 129S4/SvJae | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The loxP site flanked STOP cassette was removed from Trp53tm2Tyj via Cre-mediated recombination, allowing the expression of a p.R172H missense mutation (G>A) in exon 5. Quantitative RT-PCR confirmed that the point mutation allele is expressed at a level comparable to wild-type. |
