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Allele : Trp53<tm3.1Tyj> transformation related protein 53; targeted mutation 3.1, Tyler Jacks

Primary Identifier  MGI:3039266 Allele Type  Targeted
Gene  Trp53 Transmission  Germline
Strain of Origin  129S4/SvJae Is Recombinase  false
Is Wild Type  false
molecularNote  The loxP site flanked STOP cassette was removed from Trp53tm3Tyj via Cre-mediated recombination, allowing for the expression of the p.R270H missense mutation in exon 8. Quantitative RT-PCR confirmed that the point mutation allele was expressed at a level comparable to wild-type.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • p53<H>,
  • p53<R270H>,
  • Trp53<R270H>,
  • p53 R270H,
  • Trp53<R270H>,
  • p53 R270H,
  • p53<R270H>,
  • p53<H>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

28 Publication categories