| Primary Identifier | MGI:3039266 | Allele Type | Targeted |
| Gene | Trp53 | Transmission | Germline |
| Strain of Origin | 129S4/SvJae | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The loxP site flanked STOP cassette was removed from Trp53tm3Tyj via Cre-mediated recombination, allowing for the expression of the p.R270H missense mutation in exon 8. Quantitative RT-PCR confirmed that the point mutation allele was expressed at a level comparable to wild-type. |