Primary Identifier | MGI:3039269 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Llgl1 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The floxed exon in Llglhtm1Vv was removed via cre-mediated recombination, leaving a single LoxP site in its place. The deletion resulted in a frame shift in translation of the protein, which is predicted to disrupt translation after the first 27 amino acids that do not encode any known domains. Western blot analysis from mutants showed no protein was present. |