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Allele : Tg(CTSG-PML/RARA)#Ppp transgene insertion, Pier Paolo Pandolfi

Primary Identifier  MGI:3040508 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(CTSG-PML/RARA)#Ppp
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
description  Transgenic mice were derived from two founder lines (No. 6179 and 6380). The test population in the original study was composed of offspring from both founders.
molecularNote  The transgene expresses a fusion protein: the N-terminal 530 amino acids of PML fused to the C-terminal 402 amino acids of RARA. Transgene expression is driven by the human cathepsin G (CTSG) promoter. The pound symbol (#) is used when line is not specified and/or lines are pooled.
  • mutations:
  • Insertion
  • synonyms:
  • hCG-PML-RARalpha TG,
  • hCG-PML-RARalpha TG
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

9 Publication categories