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Allele : Dnaja3<tm1.2Jdl> DnaJ heat shock protein family (Hsp40) member A3; targeted mutation 1.2, Jiing-Dwan Lee

Primary Identifier  MGI:3040718 Allele Type  Targeted
Attribute String  Null/knockout Gene  Dnaja3
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  Cre-mediated recombination removed the floxed exon 2 in Dnaja3tm1Jdl, creating a frame-shift that putatively disrupted translation of the Dnaj domain, a glycine-and phenylalanine-rich region, a systein-rich part resembling a zinc finger, and a nonhomologous C-terminal domain. Western blot of mutant MEFs demonstrated that protein production was abolished.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Td1<->,
  • Td1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories