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Allele : Ccnf<tm1.1Sje> cyclin F; targeted mutation 1.1, Stephen J Elledge

Primary Identifier  MGI:3040863 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ccnf
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  Floxed exon 2 and neo cassette are removed following transient Cre-mediated recombination, leaving a single loxP site. Removal of exon 2 putatively generates a null mutation by preventing the encoding of F box as well as the creation of a frameshift mutation and a premature stop codon after encoding 5 amino acids and 39 amino acids, respectively. PCR confirmed recombination.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Cycf<->,
  • Cycf<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories