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Allele : Vangl2<ska17> VANGL planar cell polarity 2; skeletal/axial 17

Primary Identifier  MGI:3038827 Allele Type  Chemically induced (ENU)
Gene  Vangl2 Inheritance Mode  Recessive
Strain of Origin  C57BL/6Brd-Tyr<c-Brd> Is Recombinase  false
Is Wild Type  false Project Collection  Mutagenesis for Dev. Defects
molecularNote  A missense mutation that alters a G to a T at position 776 in the cDNA which changes arginine 259 to leucine was induced by ENU treatment. Western blot analysis indicated protein levels in the brains of homozygous mice at E16.5 were about 90% that of wild-type littermates.
  • mutations:
  • Single point mutation
  • synonyms:
  • ska<m17Jus>,
  • Vangl2<R259L>,
  • Vangl2<R259L>,
  • Lp<m2Jus>,
  • ska<m17Jus>,
  • Lp<m2Jus>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories