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Allele : Zfp148<tm1Kii> zinc finger protein 148; targeted mutation 1, Ken-ichi Isobe

Primary Identifier  MGI:3040891 Allele Type  Targeted
Attribute String  Null/knockout Gene  Zfp148
Transmission  Chimeric Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
description  Haploinsufficiency of Zfp148 prevents genetic transmission of the mutated allele and generation of non-chimeric heterozygous mice. All phenotype data reported are from chimeric mice.
molecularNote  Exon 9, which makes up over 60% of the coding region, was replaced with a neo cassette via homologous recombination. Northern blot analysis showed decreased expression in heterozygous stem cells.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories