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Allele : Angpt2<tm1Gdy> angiopoietin 2; targeted mutation 1, George D Yancopoulos

Primary Identifier  MGI:3040929 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Angpt2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A lacZ and neo cassette was inserted into the first exon, deleting 310 bp of exon 1, spanning the translation initiation site and the first 257 bp (85 codons). Lack of transcript was confirmed by Northern blot of mutant heart, kidney and lung. Beta-galactosidase was expressed from this allele under the control of the endogenous promoter.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Ang-2/LacZ,
  • Ang2<->,
  • Angpt2-,
  • Ang2<->,
  • Ang-2<->,
  • Ang-2<->,
  • Ang2<LZ>,
  • Angpt2-,
  • Ang2<LZ>,
  • Ang-2/LacZ
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

25 Publication categories