First Author | Womack JE | Year | 1981 |
Journal | Science | Volume | 212 |
Issue | 4490 | Pages | 63-5 |
PubMed ID | 7209520 | Mgi Jnum | J:6480 |
Mgi Id | MGI:54956 | Doi | 10.1126/science.7209520 |
Citation | Womack JE, et al. (1981) Gene for neuraminidase activity on mouse chromosome 17 near h-2: pleiotropic effects on multiple hydrolases. Science 212(4490):63-5 |
abstractText | The low activity of liver neuraminidase that is characteristic of mouse strain SM/J is inherited as a single gene on chromosome 17, near the major histocompatibility complex. This gene, neuraminidase-1 (Neu-1), is represented by the low activity allele Neu-1s in SM/J and the high activity allele Neu-1b in C57BL/6J and most other strains. Previously described variations in the posttranslational processing of acid phosphatase, alpha-mannosidase, arylsulfatase-B, and alpha-glucosidase are attributed to pleiotropic effects of this gene. |