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Publication : Gene for neuraminidase activity on mouse chromosome 17 near h-2: pleiotropic effects on multiple hydrolases.

First Author  Womack JE Year  1981
Journal  Science Volume  212
Issue  4490 Pages  63-5
PubMed ID  7209520 Mgi Jnum  J:6480
Mgi Id  MGI:54956 Doi  10.1126/science.7209520
Citation  Womack JE, et al. (1981) Gene for neuraminidase activity on mouse chromosome 17 near h-2: pleiotropic effects on multiple hydrolases. Science 212(4490):63-5
abstractText  The low activity of liver neuraminidase that is characteristic of mouse strain SM/J is inherited as a single gene on chromosome 17, near the major histocompatibility complex. This gene, neuraminidase-1 (Neu-1), is represented by the low activity allele Neu-1s in SM/J and the high activity allele Neu-1b in C57BL/6J and most other strains. Previously described variations in the posttranslational processing of acid phosphatase, alpha-mannosidase, arylsulfatase-B, and alpha-glucosidase are attributed to pleiotropic effects of this gene.
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