Primary Identifier | MGI:3043142 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Robo1 |
Transmission | Germline | Strain of Origin | 129X1/SvJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The third intron was disrupted by the insertion of a PLAP secretory gene trap vector containing a splice acceptor site followed by Beta-geo, an IRES, placental alkaline phosphatase, and a PGK-1 polyA tail. Some residual RNA expression is seen in RNA protection analysis, however in immunostaining analysis no protein is detected in homozygous mutant mice. |