Primary Identifier | MGI:3042842 | Allele Type | Targeted |
Attribute String | Humanized sequence, Inserted expressed sequence, Null/knockout | Gene | Otx2 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd-Hprt1<b-m3> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A human OTX1 cDNA flanked by the Otx2 5' and 3' UTR's replaced all the coding sequence and introns. Only 50 bp of poladenylation signal is duplicated in this allele. This allele expresses the human OTX1 protein under Otx2 transcriptional control. |