Primary Identifier | MGI:3043369 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Gnas |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The floxed fragment from -6267 to -1601 bp upstream of the translation start site was excised via Cre mediated recombination in vivo, resulting in the deletion of Gnas exon 1A regulatory region which regulates tissue-specific imprinting of Gs-alpha. |