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Allele : Hsf1<tm1Anak> heat shock factor 1; targeted mutation 1, Akira Nakai

Primary Identifier	MGI:3044161	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Hsf1
Transmission	Germline	Strain of Origin	(C57BL/6NCrlj x CBA/JNCrlj)F1
Is Recombinase	false	Is Wild Type	false

molecularNote

Exons 2-4 were replaced with a neo cassette. Exons 2 and 3 encode the DNA-binding domain. Southern blot confirmed recombination.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

earliestPublication:
Inouye S, et al. (2003) Activation of heat shock genes is not necessary for protection by heat shock transcription factor 1 against cell death due to a single exposure to high temperatures. Mol Cell Biol 23(16):5882-95

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

33 Publication categories

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