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Allele : Gck<Gena348> glucokinase; Gena348, Harwell

Primary Identifier  MGI:3044558 Allele Type  Chemically induced (ENU)
Gene  Gck Inheritance Mode  Dominant
Strain of Origin  BALB/c Is Recombinase  false
Is Wild Type  false
molecularNote  An A to T transversion is found at position 1096 in exon 9. This results in a missense amino acid change from isoleucine to phenylalanine at position 366. Western blot analysis did not find any significant change in protein expression although glucose phosphorylating activity was significantly impaired. This mutation was generated as part of the Harwell/SB ENU mutagenesis project.
  • mutations:
  • Single point mutation
  • synonyms:
  • Gck<I366F>,
  • Gck<I366F>,
  • Gena348,
  • Gena348
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

8 Publication categories