| Primary Identifier | MGI:3043774 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Anp32a |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted upstream of eoxn 2. A floxed neo cassette was inserted downstream of exon 3. Cre-mediated recombination removed exon 2, exon 3, and the neo cassette. Aberrant splicing between exons 1 and 4 is predicted to produce a premature stop codon in exon 4 due to a frameshift. The absence of protein expression was confirmed by western blot analysis of cerebellar extracts. |
