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Allele : Runx2<tm1Ldq> runt related transcription factor 2; targeted mutation 1, L Darryl Quarles
Primary Identifier  MGI:3043791 Allele Type  Targeted
Attribute String  Null/knockout Gene  Runx2
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  The P1 promoter and exon 1 were replaced with a neo cassette via homologous recombination. This specifically deleted the Runx2-II isoform and not the Runx2-I isoform. Rt-PCR confirmed the absence of Runx2-II RNA and the presence of Runx2-I RNA.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Runx2-II-,
  • Runx2-II-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

7 Publication categories





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