| First Author | Teh HS | Year | 1988 |
| Journal | Nature | Volume | 335 |
| Issue | 6187 | Pages | 229-33 |
| PubMed ID | 2970593 | Mgi Jnum | J:79755 |
| Mgi Id | MGI:2388881 | Doi | 10.1038/335229a0 |
| Citation | Teh HS, et al. (1988) Thymic major histocompatibility complex antigens and the alpha beta T-cell receptor determine the CD4/CD8 phenotype of T cells. Nature 335(6187):229-33 |
| abstractText | T-cell receptors and T-cell subsets were analysed in T-cell receptor transgenic mice expressing alpha and beta T-cell receptor genes isolated from a male-specific, H-2Db-restricted CD4-8+ T-cell clone. The results indicate that the specific interaction of the T-cell receptor on immature thymocytes with thymic major histocompatibility complex antigens determines the differentiation of CD4+8+ thymocytes into either CD4+8- or CD4-8+ mature T cells. |
