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Allele : Scn1b<tm1Isom> sodium channel, voltage-gated, type I, beta; targeted mutation 1, Lori L Isom

Primary Identifier  MGI:3043422 Allele Type  Targeted
Attribute String  Null/knockout Gene  Scn1b
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 3 as well as the 73 bp of intron 3 that are required for the expression of the Beta1A embryonic splice variant were replaced by a neomycin cassette inserted by homologous recombination. Transcript was undetected in homozygous mutant mice by Northern blot analysis of brain RNA.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Beta1 (-),
  • Beta1 (-)
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

25 Publication categories